Toxno Substance Profile
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Substance Name

Identification Number: CASRN | 127277-53-6

  Substance Attributes

  • No Nastiness Attributes Yet

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  • CATEGORIES: Industrial/Workplace Toxin | Synthetic Toxin | PESTICIDE active ingredient | Pesticide or Plant Growth Regulator Approved in Australia | Pesticide approved in USA (California)
  • SUBSTANCE LINEAGE: Organic Compounds | Organooxygen Compounds | Carbonyl Compounds | Ketones | Cyclohexanones
  • SYNONYMS: 3,5-Dioxo-4-propionyl-cyclohexanecarboxylic acid calcium salt | Calcium bis(3,5-dioxo-4-propanoylcyclohexanecarboxylate) | Calcium bis(3,5-dioxo-4-propionylcyclohexanecarboxylate)
  • DESCRIPTION: Prohexadione-calcium is a plant growth regulator that inhibits gibberellin metabolism. It is frequently used as a growth-retardant compound for apples. Prohexidione-calcium is known to reduce terminal growth by inhibiting 2-oxoglutarate-dependent dioxygenases, which are involved in the formation of growth-specific gibberellins (e.g., the conversion of GA20 to GA1), a group of plant hormones that are primarily responsible for regulation of shoot elongation in apple trees. In addition, it is also known that prohexadione-calcium interferes with ethylene biosynthesis and flavonoid metabolism, which can influence other responses in the plant.
  • COMMENTS: Residues of this pesticide are tested for on Australian Foods | Pesticide approved in Australia
  • toxin chemical structure pubchem
  • FORMULA: C20H22CaO10
  • DATA SOURCES: DATA SOURCES: T3DB | PubChem | Compendium of Pesticide Common Names | APVMA | DPR
  • LAST UPDATE: 28/04/2018

  Health Associations

Mostly focused on Health Implications of Long Term Exposure to this substance

  • TOXIN SITES OF ACTION IN CELL: "Cytoplasm", "Extracellular"
  • Additional Exposure Routes:

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  Exposure Routes

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