Toxno Substance Profile
Evidence-based data. We have more than 25,000 profiles on Toxno.
Use Search below to seek out more. Or browse the Exposure Routes; alternatively see our Lists that have more substances than notes in a Liszt virtuoso piano piece.
Substance Name

Ethyl cyanoacrylate
Identification Number: CASRN | 7085-85-0

  Substance Attributes


  • Metabolic Interference or Disruption

    Interferes with human metabolism. This can be a very serious thing. Some of these interference mechanics are well established. However, often long term effects and health consequences remain largely unknown. Additionally an emerging area of concern and one that is not currently studied, is the combined synergistic effects these metabolically disrupting chemicals have on human health.


    Metabolic interference happens when the substance produces highly reactive and often damaging intermediates during detoxification or when the substance binds to specific enzymes, important structural groups on molecules, receptors and membranes or targets DNA or mimics key nutrients.

  • Exposure Produces Health Symptoms

    Symptoms maybe short term or long term depending on the exposure duration and intensity and effects areas like Cardiovascular, Gastrointestinal, Cognition, Fatigue. A substance with this attribute may cause an allergic skin reaction, serious eye irritation, allergy or asthma symptoms or breathing difficulties if inhaled.

These attributes are ONLY based on peer-reviewed evidence. See link to Data Sources below. Everyone benefits from knowing this stuff. Please Share.



  • CATEGORIES: Household Toxin | Industrial/Workplace Toxin | Synthetic Toxin | A Hazardous Substance that may be found in the Australian Workplace
  • SUBSTANCE LINEAGE: Organic Compounds | Organic Acids and Derivatives | Carboxylic Acids and Derivatives | Carboxylic Acid Derivatives | Enones
  • SYNONYMS: 2-Cyano-2-propenoic acid | ethylester | homopolymer | 2-Propenoic acid | 2-cyano- | ethyl ester | 2-Propenoic acid | 2-cyano- | ethyl ester | homopolymer | Acrylic acid | 2-cyano- | ethyl ester | Cyacrin | Cyacrine | Cyano-veneer | Ethyl 2-cyanoacrylate | Ethyl cyanoacrylic acid | ethyl-2-cyanoacrylate | Krazy glue | Poly(ethyl 2-cyanoacrylate)
  • DESCRIPTION: Ethyl cyanoacrylate is a chemical compound of cyanide. It is used as the main component of certain cyanoacrylate glues, such as the well known Super Glue and Krazy Glue. (L605)
  • COMMENTS:

    From Safe Work Australia and the Hazardous Substances Information System (HSIS) in Australia:

    Causes serious eye irritation. May cause respiratory irritation. Causes skin irritation | General Health Hazard | A Hazardous Substance that may be found in the Australian Workplace. Check with your employer or health and safety officer. Stay informed and become aware of the dangers that surround you. This chemical is included on the list of recognised hazardous chemicals from the Safe Work Australia - Hazardous Substances Information System (HSIS) that is based on the Globally Harmonised System of Classification and Labelling of Chemicals (GHS)

    Work Health and Safety (WHS) Regulations are the basis for hazardous chemicals regulations in Commonwealth, State and Territory jurisdictions in Australia. Under the model WHS Regulations, manufacturers and importers of substances, mixtures and articles supplied for use in workplaces are required to determine whether they are hazardous to health and safety before supply. The model WHS Regulations mandate that the hazards of a chemical as determined by the Globally Harmonised System of Classification and Labelling of Chemicals (GHS) must be included in safety data sheets and on labels. There are transitional arrangements in place for moving to the GHS-based system.

    The GHS Hazardous Chemical Information List contains chemicals classified by an authoritative source (such as the European Commission or NICNAS) in accordance with the Globally Harmonized System of Classification and Labelling of Chemicals (the GHS). This list contains the vast majority of chemicals currently in HSIS. This list and its detail are regularly updated by Work Safe Australia. The model Work Health and Safety (WHS) Regulations require chemicals to be classified in accordance with the Globally Harmonised System of Classification and Labelling of Chemicals (GHS). However transitional arrangements allow use of classification information in HSIS derived from the Approved Criteria until the 31 December 2016.
  • toxin chemical structure pubchem
  • FORMULA: C6H7NO2
  • DATA SOURCES: DATA SOURCES: ARTICLE 4 | T3DB | PubChem | Safe Work Australia - Hazardous Substances Information System (HSIS)
  • LAST UPDATE: 28/04/2018

  Health Associations

Mostly focused on Health Implications of Long Term Exposure to this substance

  • SYMPTOMS: Cyanide poisoning is identified by rapid, deep breathing and shortness of breath, general weakness, giddiness, headaches, vertigo, confusion, convulsions/seizures and eventually loss of consciousness. (L96, L97)
  • POSSIBLE HEALTH CONSEQUENCES: Exposure to high levels of cyanide for a short time harms the brain and heart and can even cause coma, seizures, apnea, cardiac arrest and death. Chronic inhalation of cyanide causes breathing difficulties, chest pain, vomiting, blood changes, headaches, and enlargement of the thyroid gland. Skin contact with cyanide salts can irritate and produce sores. (L96, L97) | Organic nitriles are converted into cyanide ions through the action of cytochrome P450 enzymes in the liver. Cyanide is rapidly absorbed and distributed throughout the body. Cyanide is mainly metabolized into thiocyanate by either rhodanese or 3-mercaptopyruvate sulfur transferase. Cyanide metabolites are excreted in the urine. (L96)
  • ACTION OF TOXIN: Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxic cyanide ions or hydrogen cyanide. Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). It complexes with the ferric iron atom in this enzyme. The binding of cyanide to this cytochrome prevents transport of electrons from cytochrome c oxidase to oxygen. As a result, the electron transport chain is disrupted and the cell can no longer aerobically produce ATP for energy. Tissues that mainly depend on aerobic respiration, such as the central nervous system and the heart, are particularly affected. Cyanide is also known produce some of its toxic effects by binding to catalase, glutathione peroxidase, methemoglobin, hydroxocobalamin, phosphatase, tyrosinase, ascorbic acid oxidase, xanthine oxidase, succinic dehydrogenase, and Cu/Zn superoxide dismutase. Cyanide binds to the ferric ion of methemoglobin to form inactive cyanmethemoglobin. (L97) | Cyanide inhibits alkaline phosphatases. (A73)
  • TOXIN SITES OF ACTION IN CELL: "Cytoplasm", "Extracellular"
  • Additional Exposure Routes: Ethyl cyanoacrylate is used as the main component of certain cyanoacrylate glues, such as the well known Super Glue and Krazy Glue. (L605)

 Search all of Toxno

Or browse our mind blowing but terrifying Lists.

  Exposure Routes

These are the Exposure Routes we have so far for this substance. There are almost certainly more. We update this section regularly. The number of chemicals with 2 or more nastiness attributes in an exposure route is shown in orange. They grey badge shows the total amount of chemicals within the exposure route.


  Stay Informed

Chemicals released in consumer products and the environment are constantly changing. Regulations change. Exposure Routes change. People speak up and nasties are removed while often others are introduced.

By signing up you will periodically receive updates of potentially life changing information. Both for yourself and your family.

We take security and privacy very seriously and you can unsubscribe at any time.


cats at toxno

"Yeh. We were surprised too"