Toxno Substance Profile
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Substance Name

Diethanolamine
Identification Number: CASRN | 111-42-2

  Substance Attributes


  • Known Human Carcinogen

    This is a serious nasty substance. Exposure to this substance leads to cancer in Humans. Exercise extreme caution with this substance, explore your exposure routes and very seriously consider complete avoidance. See further details under Toxins.

  • Carcinogenic Properties

    Accumulating evidence points to cancer potential. Exercise caution with this substance, explore your exposure routes and consider complete avoidance. See further details under Toxins.

  • Endocrine Disrupter

    Interferes with your hormones. Hormones are powerful messengers that can bind to DNA. You don't want to mess with them.

  • Mutagenic Properties

    Cause mutations to Genetic material like DNA, RNA or mitochondrial DNA

  • Reproductive Effects

    Interferes with fertility

  • Birth/Developmental

    Known to effect development of fetus.

  • Exposure Produces Health Symptoms

    Symptoms maybe short term or long term depending on the exposure duration and intensity and effects areas like Cardiovascular, Gastrointestinal, Cognition, Fatigue. A substance with this attribute may cause an allergic skin reaction, serious eye irritation, allergy or asthma symptoms or breathing difficulties if inhaled.

  • Toxic to specific organs

    Can damage liver, kidney, lungs, heart or gut. Ironically liver, kidneys and gut are the main detoxifications systems.

  • Soluble in Water

    This substance easily dissolves in water. As such it can be easily transported via waterways. Not really a nastiness attribute, but this feature helps rapidly spread other nastiness attributes this substance may have.

  • Volatile - Evaporates easily

    This substance easily enters the air we breath. Not really a nastiness attribute, but this feature helps rapidly spread other nastiness attributes this substance may have.

These attributes are ONLY based on peer-reviewed evidence. See link to Data Sources below. Everyone benefits from knowing this stuff. Please Share.



  • CATEGORIES: Drilling Chemicals, CSG - The information here is based on chemicals used in drilling a natural gas well, Crosby 25-3, in Park County, Wyoming. Natural gas, petroleum condensate, and drilling fluids were accidentally released from the ground adjacent to the well due to a breach in the surface casing. This occurred over a period of about 58 hours between August 11 and 13th, 2006. | Chemicals used in hydraulic fracturing fluids | Household Toxin | Industrial/Workplace Toxin | Pollutant | Airborne Pollutant | Food Toxin | Synthetic Toxin | Indirect Additives Used in Food Contact Substances | PESTICIDE active ingredient | Inert Pesticide Ingredient USA - Food Use Permitted | Pesticide approved in USA (California) | A Hazardous Substance that may be found in the Australian Workplace
  • SUBSTANCE LINEAGE: Organic Compounds | Organonitrogen Compounds | Amines | Alkanolamines | 1,2-Aminoalcohols
  • SYNONYMS: 2,2'-Dihydroxydiethylamine | 2,2'-Iminobis | 2,2'-Iminobisethanol | 2,2'-Iminodi-1-ethanol | 2,2'-Iminodiethanol | 2,2'Iminobisethanol | 2-(2-Hydroxyethylamino)ethanol | 2-[(2-Hydroxyethyl)amino]ethanol | Aliphatic amine | Bis(2-hydroxyethyl)amine | Bis(2-hydroxyethyl)tallow amine oxide | Bis(hydroxyethyl)amine | Bis-2-hydroxyethylamine | DEA | Di(2-hydroxyethyl)amine | Di(beta-hydroxyethyl)amine | Diaethanolamin | Diethanolamin | Diethylolamine | Dihydroxyethyl tallowamine oxide | Diolamine | H2dea | Iminodiethanol | N,N'-Iminodiethanol | N,N-Bis(2-hydroxyethyl)amine | N,N-Di(hydroxyethyl)amine | N,N-Diethanolamine | Niax DEOA-LF
  • DESCRIPTION: Has been used in CSG, Hydraulic Fracturing Operations (Fracking) as - Detergent, lubricant, fracturing, unknown, corrosion inhibitor | Diethanolamine, often abbreviated as DEA, is an organic chemical compound which is both a secondary amine and a dialcohol. A dialcohol has two hydroxyl groups in its molecule. Like other amines, diethanolamine acts as a weak base. Diethanolamine is widely used in the preparation of diethanolamides and diethanolamine salts of long-chain fatty acids that are formulated into soaps and surfactants used in liquid laundry and dishwashing detergents, cosmetics, shampoos, and hair conditioners. Diethanolamine is also used in textile processing, in industrial gas purification to remove acid gases, as an anticorrosion agent in metalworking fluids, and in preparations of agricultural chemicals. Aqueous diethanolamine solutions are used as solvents for numerous drugs that are administered intravenously.
  • COMMENTS:

    From Safe Work Australia and the Hazardous Substances Information System (HSIS) in Australia:

    Harmful if swallowed. May cause damage to organs through prolonged or repeated exposure . Causes skin irritation. Causes serious eye damage | Chronic Health Hazard General Health Hazard | A Hazardous Substance that may be found in the Australian Workplace. Check with your employer or health and safety officer. Stay informed and become aware of the dangers that surround you. This chemical is included on the list of recognised hazardous chemicals from the Safe Work Australia - Hazardous Substances Information System (HSIS) that is based on the Globally Harmonised System of Classification and Labelling of Chemicals (GHS)

    Work Health and Safety (WHS) Regulations are the basis for hazardous chemicals regulations in Commonwealth, State and Territory jurisdictions in Australia. Under the model WHS Regulations, manufacturers and importers of substances, mixtures and articles supplied for use in workplaces are required to determine whether they are hazardous to health and safety before supply. The model WHS Regulations mandate that the hazards of a chemical as determined by the Globally Harmonised System of Classification and Labelling of Chemicals (GHS) must be included in safety data sheets and on labels. There are transitional arrangements in place for moving to the GHS-based system.

    The GHS Hazardous Chemical Information List contains chemicals classified by an authoritative source (such as the European Commission or NICNAS) in accordance with the Globally Harmonized System of Classification and Labelling of Chemicals (the GHS). This list contains the vast majority of chemicals currently in HSIS. This list and its detail are regularly updated by Work Safe Australia. The model Work Health and Safety (WHS) Regulations require chemicals to be classified in accordance with the Globally Harmonised System of Classification and Labelling of Chemicals (GHS). However transitional arrangements allow use of classification information in HSIS derived from the Approved Criteria until the 31 December 2016.
  • toxin chemical structure pubchem
  • FORMULA: C4H11NO2
  • DATA SOURCES: DATA SOURCES: ARTICLE 4 | T3DB | PubChem | IARC | OEHHA | Article-Colborn-2010 | FracFocus | US HOUSE OF REPRESENTATIVES | FDA Indirect Food Additives | DPR | EPA USA - Pesticide Inerts | Safe Work Australia - Hazardous Substances Information System (HSIS)
  • LAST UPDATE: 28/04/2018

  Health Associations

Mostly focused on Health Implications of Long Term Exposure to this substance

  • SYMPTOMS:
  • POSSIBLE HEALTH CONSEQUENCES:
  • ACTION OF TOXIN:
  • TOXIN SITES OF ACTION IN CELL: "Cytoplasm", "Extracellular"
  • Additional Exposure Routes:

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  Exposure Routes

These are the Exposure Routes we have so far for this substance. There are almost certainly more. We update this section regularly. The number of chemicals with 2 or more nastiness attributes in an exposure route is shown in orange. They grey badge shows the total amount of chemicals within the exposure route.


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