Toxno Substance Profile
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Substance Name

Potassium Chloride
Identification Number: CASRN | 7447-40-7

  Substance Attributes


  • Endocrine Disrupter

    Interferes with your hormones. Hormones are powerful messengers that can bind to DNA. You don't want to mess with them.

  • Metabolic Interference or Disruption

    Interferes with human metabolism. This can be a very serious thing. Some of these interference mechanics are well established. However, often long term effects and health consequences remain largely unknown. Additionally an emerging area of concern and one that is not currently studied, is the combined synergistic effects these metabolically disrupting chemicals have on human health.


    Metabolic interference happens when the substance produces highly reactive and often damaging intermediates during detoxification or when the substance binds to specific enzymes, important structural groups on molecules, receptors and membranes or targets DNA or mimics key nutrients.

  • Toxic to specific organs

    Can damage liver, kidney, lungs, heart or gut. Ironically liver, kidneys and gut are the main detoxifications systems.

  • Soluble in Water

    This substance easily dissolves in water. As such it can be easily transported via waterways. Not really a nastiness attribute, but this feature helps rapidly spread other nastiness attributes this substance may have.

  • Has known Side Effects

    This is often the result of long or short term medication use. The same medication can have a range of side effects ranging from none at all to totally debilitating symptoms within different individuals. Reasons for this include individual genetics, individual detoxification capacity, nutrition status, duration of use and total number of medications being taken.


    It becomes very difficult to establish clear causes of symptoms when multiple medications are being taken at once.


    See SIDE EFFECTS LINKOUT at end of this profile.

These attributes are ONLY based on peer-reviewed evidence. See link to Data Sources below. Everyone benefits from knowing this stuff. Please Share.



  • CATEGORIES: Food Additives with E Numbers | Mineral salts | Chemical used in hydraulic fracturing fluids | Medication or Drug | Household Toxin | Food Toxin | Natural Toxin | EAFUS (Everything Added to Food in the United States) | Inert Pesticide Ingredient USA - Food Use Permitted | Medication Approved in Australian (on the PBS) | Medication Approved in USA
  • SUBSTANCE LINEAGE: Inorganic Compounds | Mixed Metal/Non-metal Compounds | Alkali Metal Salts | Alkali Metal Chlorides | Alkali Metal Chlorides
  • SYNONYMS: Chlorid draselny | Chloride of potash | K-Dur | K-Tab | Kaliumchlorid | Kaon Cl | Kaon-CL 10 | KCl | Klor-CON | Klotrix | Micro-K | Monopotassium chloride | Muriate of potash | Potassium chloride | Sando-K | Slow-K | Sylvite | [KCl]
  • DESCRIPTION: E Number: E508 | Food Additives with E Numbers used in Australia, NZ, UK and the EU. Over 400 in total. | Substance has been approved in: Australia and NZ | EU and UK | | Mineral salts | Natural occurring chemical often associated with rock salt. Used as an emulsifier, stabiliser, salt substitute and dietary supplement. | Found in low sodium or salt products. | Has been used in CSG, Hydraulic Fracturing Operations (Fracking) as - pH control, reagent, cement accelerator, clay control, unknown, fracturing | A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
  • COMMENTS:
  • toxin chemical structure pubchem
  • FORMULA: ClK
  • DATA SOURCES: DATA SOURCES: ARTICLE 4 | T3DB | PubChem | Article-Colborn-2010 | FracFocus | EPA in USA | US HOUSE OF REPRESENTATIVES | APPEA | FSANZ and FSA | EAFUS | EPA USA - Pesticide Inerts | Drugbank | Australian Approved Medications PBS | USA FDA APPROVED DRUG PRODUCTS
  • LAST UPDATE: 28/04/2018

  Health Associations

Mostly focused on Health Implications of Long Term Exposure to this substance

  • SYMPTOMS:
  • POSSIBLE HEALTH CONSEQUENCES: The administration of oral potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. However, if excretory mechanisms are impaired, of if potassium is administered too rapidly intravenously, potentially fatal hyperkalemia can result. It is important to recognize that hyperkalemia is usually asymptomatic and may be manifested only by an increased serum potassium concentration (6.5-8.0 mEq/L) and characteristic electrocardiographic changes (peaking of T-waves, loss of P-wave, depression of S-T segment, and prolongation of the QT interval). Late manifestations include muscle paralysis and cardiovascular collapse from cardiac arrest (9-12 mEq/L). | Route of Elimination: Potassium is a normal dietary constituent and, under steady-state conditions, the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine. Potassium depletion will occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake.
  • ACTION OF TOXIN: Supplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels. |
  • TOXIN SITES OF ACTION IN CELL: "Cytoplasm", "Extracellular"
  • Additional Exposure Routes: For use as an electrolyte replenisher and in the treatment of hypokalemia.
  • SEE MEDICATION SIDE EFFECTS

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  Exposure Routes

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