Toxno Substance Profile
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Substance Name

Oxybenzone
Identification Number: CASRN | 131-57-7

  Substance Attributes


  • Metabolic Interference or Disruption

    Interferes with human metabolism. This can be a very serious thing. Some of these interference mechanics are well established. However, often long term effects and health consequences remain largely unknown. Additionally an emerging area of concern and one that is not currently studied, is the combined synergistic effects these metabolically disrupting chemicals have on human health.


    Metabolic interference happens when the substance produces highly reactive and often damaging intermediates during detoxification or when the substance binds to specific enzymes, important structural groups on molecules, receptors and membranes or targets DNA or mimics key nutrients.

  • Has known Side Effects

    This is often the result of long or short term medication use. The same medication can have a range of side effects ranging from none at all to totally debilitating symptoms within different individuals. Reasons for this include individual genetics, individual detoxification capacity, nutrition status, duration of use and total number of medications being taken.


    It becomes very difficult to establish clear causes of symptoms when multiple medications are being taken at once.


    See SIDE EFFECTS LINKOUT at end of this profile.

These attributes are ONLY based on peer-reviewed evidence. See link to Data Sources below. Everyone benefits from knowing this stuff. Please Share.



  • CATEGORIES: Medication or Drug | Household Toxin | Synthetic Toxin | Indirect Additives Used in Food Contact Substances | PESTICIDE active ingredient | Inert Pesticide Ingredient USA - Non Food Use Only | Pesticide or Plant Growth Regulator Approved in Australia
  • SUBSTANCE LINEAGE: Organic Compounds | Benzenoids | Benzene and Substituted Derivatives | Benzophenones | Benzophenones
  • SYNONYMS: (2-Hydroxy-4-methoxyphenyl)phenylmethanone | 2-Benzoyl-5-methoxyphenol | 2-Hydroxy-4-methoxybenzophenone | 4-Methoxy-2-hydroxybenzophenone | 4-Methoxy-2-hydroxybenzophenone butyric acid | Benzophenone-3 | Oxibenzona | Oxybenzonum
  • DESCRIPTION: Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
  • COMMENTS: Residues of this pesticide are NOT tested for on Australian Foods even though the Pesticide is approved in Australia. This is partly so because this pesticide is not usually used around food agriculture. | Pesticide approved in Australia
  • toxin chemical structure pubchem
  • FORMULA: C14H12O3
  • DATA SOURCES: DATA SOURCES: ARTICLE 4 | T3DB | PubChem | FDA Indirect Food Additives | APVMA | EPA USA - Pesticide Inerts | Drugbank | USA FDA APPROVED DRUG PRODUCTS
  • LAST UPDATE: 28/04/2018

  Health Associations

Mostly focused on Health Implications of Long Term Exposure to this substance

  • SYMPTOMS:
  • POSSIBLE HEALTH CONSEQUENCES: | Route of Elimination: In vivo studies show oxybenzone is abosorbed transdermally (through the skin) and is excreted in the urine.
  • ACTION OF TOXIN: Oxybenzone absorbs UV-A ultraviolet rays, preventing them from reaching the skin. |
  • TOXIN SITES OF ACTION IN CELL: "Membrane"
  • Additional Exposure Routes: Used as an ingredient in sunscreen and other cosmetics.
  • SEE MEDICATION SIDE EFFECTS

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  Exposure Routes

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