Toxno Substance Profile
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Substance Name

Piperonyl butoxide
Identification Number: CASRN | 51-03-6

  Substance Attributes


  • Carcinogenic Properties

    Accumulating evidence points to cancer potential. Exercise caution with this substance, explore your exposure routes and consider complete avoidance. See further details under Toxins.

These attributes are ONLY based on peer-reviewed evidence. See link to Data Sources below. Everyone benefits from knowing this stuff. Please Share.



  • CATEGORIES: Pesticide | Household Toxin | Synthetic Toxin | Indirect Additives Used in Food Contact Substances | PESTICIDE active ingredient | organic | insecticide synergists | Inert Pesticide Ingredient USA - Non Food Use Only | Pesticide or Plant Growth Regulator Approved in Australia | Pesticide approved in USA (California)
  • SUBSTANCE LINEAGE: Organic Compounds | Heterocyclic Compounds | Benzodioxoles | | Benzodioxoles
  • SYNONYMS: (3,4-Methylenedioxy-6-propylbenzyl) (butyl) diethylene glycol ether | (Butylcarbityl)(6-propylpiperonyl)ether | 2-(2-Butoxyethoxy)ethyl 6-propylpiperonyl ether | 5-Propyl-4-(2,5,8-trioxa-dodecyl)-1,3-benzodioxole | 6-Propylpiperonyl butyl diethylene glycol ether | alpha-(2-(2-N-Butoxyethoxy)-ethoxy)-4,5-methylenedioxy-2-propyltoluene | alpha-[2-(2-Butoxyethoxy)ethoxy]-4,5-(methylenedioxy)-2-propyltoluene | Butyl carbitol 6-propylpiperonyl ether
  • DESCRIPTION: Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is a waxy white solid. It is a synergist. That is, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as especially for carbamates, pyrethrins, pyrethroids, and rotenone. It is a semisynthetic derivative of safrole.
  • COMMENTS: Residues of this pesticide are tested for on Australian Foods | Pesticide approved in Australia
  • toxin chemical structure pubchem
  • FORMULA: C19H30O5
  • DATA SOURCES: DATA SOURCES: ARTICLE 4 | CPDB | T3DB | PubChem | IARC | FDA Indirect Food Additives | Consolidated Pesticide Information Dataset (CPI) from the USA EPA | Compendium of Pesticide Common Names | APVMA | DPR | EPA USA - Pesticide Inerts
  • LAST UPDATE: 28/04/2018

  Health Associations

Mostly focused on Health Implications of Long Term Exposure to this substance

  • SYMPTOMS:
  • POSSIBLE HEALTH CONSEQUENCES:
  • ACTION OF TOXIN:
  • TOXIN SITES OF ACTION IN CELL: "Cell surface", "Cytosol", "Endoplasmic reticulum", "Extracellular", "Membrane", "Microsome", "Microtubule", "Mitochondrial Membrane", "Mitochondrion", "Plasma Membrane"
  • Additional Exposure Routes: This is a man-made compound that is used as a pesticide.

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  Exposure Routes

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